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Laboratory characteristics of pregnant compared to non-pregnant women infected with SARS-CoV-2.
- Source :
-
Archives of Gynecology & Obstetrics . Sep2020, Vol. 302 Issue 3, p629-634. 6p. - Publication Year :
- 2020
-
Abstract
- <bold>Key Message: </bold>Laboratory characteristics of SARS-CoV-2 infection did not differ between pregnant and non-pregnant women. A trend of lower lymphocyte count was observed in the pregnant women group PURPOSE: Laboratory abnormalities, which characterize SARS-CoV-2 infection have been identified, nevertheless, data concerning laboratory characteristics of pregnant women with SARS-CoV-2 are limited. The aim of this study is to evaluate the laboratory characteristics of pregnant compared to non-pregnant women with SARS-CoV-2 infection.<bold>Methods: </bold>A retrospective cohort study of all pregnant women with SARS-CoV-2 who were examined at the obstetric emergency room in a tertiary medical center between March and April 2020. Patients were compared with non-pregnant women with SARS-CoV-2 matched by age, who were examined at the general emergency room during the study period. All patients were confirmed for SARS-CoV-2 on admission. Clinical characteristics and laboratory results were compared between the groups.<bold>Results: </bold>Study group included 11 pregnant women with SARS-CoV-2, who were compared to 25 non-pregnant controls. Respiratory complaints were the most frequent reason for emergency room visit, and were reported in 54.5% and 80.0% of the pregnant and control groups, respectively (p = 0.12). White blood cells, hemoglobin, platelets, and liver enzymes counts were within the normal range in both groups. Lyphocytopenia was observed in 45.5% and 32% of the pregnant and control groups, respectively (p = 0.44). The relative lymphocyte count to WBC was significantly reduced in the pregnant group compared to the controls [13.6% (4.5-19.3) vs. 26.5% (15.7-29.9); p = 0.003]. C-reactive protein [20(5-41) vs. 14 (2-52) mg/dL; p = 0.81] levels were elevated in both groups but without significant difference between them.<bold>Conclusion: </bold>Laboratory characteristics of SARS-CoV-2 infection did not differ between pregnant and non-pregnant women, although a trend of lower lymphocyte count was observed in the pregnant women group. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SARS-CoV-2
*LEUCOCYTES
*LYMPHOCYTE count
*PREGNANT women
*LIVER enzymes
*VIRAL pneumonia
*C-reactive protein
*RESEARCH
*COMMUNICABLE diseases
*RESEARCH methodology
*RETROSPECTIVE studies
*EVALUATION research
*MEDICAL cooperation
*CORONAVIRUSES
*COMPARATIVE studies
*PREGNANCY complications
*EPIDEMICS
*HOSPITAL care
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 09320067
- Volume :
- 302
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Archives of Gynecology & Obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 145301921
- Full Text :
- https://doi.org/10.1007/s00404-020-05655-7