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A study on the response of FRET based DNA aptasensors in intracellular environment.
- Source :
-
Scientific Reports . 8/6/2020, Vol. 10 Issue 1, p1-8. 8p. - Publication Year :
- 2020
-
Abstract
- This paper presents a study of the response of FRET based DNA aptasensors in the intracellular environment. Herein, we extend previous studies of aptasensors functioning in the extracellular environment to detection of antigens in the intracellular environment. An essential step in this research is the use of a novel means of achieving the endocytosis of aptasensors. Specifically, it is demonstrated that functioning aptasensors are successfully endocytosed by functionalizing the aptasensors with endocytosis—inducing DSS peptides. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DNA
*ANTIGENS
*EXTRACELLULAR space
*INTRACELLULAR membranes
*PEPTIDES
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Scientific Reports
- Publication Type :
- Academic Journal
- Accession number :
- 145029611
- Full Text :
- https://doi.org/10.1038/s41598-020-70261-1