ATNALI BÖBREK ANOMALİLİ ÇOCUK HASTALARIN DEĞERLENDİRİLMESİ.

INTRODUCTION: Horseshoe kidney is the most common renal fusion anomaly. Horseshoe kidneys may be a part of certain genetic syndromes and may be associated with other anatomic malformations. Urinary malformations might require surgical treatment, and might also lead to renal scar formation and therefore chronic kidney damage. In this study, we aimed to evaluate the clinical course and prognosis of horseshoe kidney in pediatric patients. MATERIALS and METHODS: Medical records of the patients with horseshoe kidneys followed in the pediatric nephrology department of University of Health Sciences, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital between January 2010 and December 2018 were retrospectively evaluated. RESULTS: Twenty-two girls (36.7%) and 38 boys (63.3%) were included in this study. Mean age of the patients were 5.3±4.2 years and mean follow up time was 38.3±3.1 months. Three patients (%5) were diagnosed prenatally. Five patients (8.3%) had extrarenal malformations, 4 patients (6,6%) had genetic syndromes. There were no significant differences in terms of serum sodium, potassium, urea, uric acid levels and creatinine clearance between the time of diagnosis and the end of the follow-up (p>0.05). Mean serum creatinine levels of the patients increased significantly at the end of the followup (p=0.02). There were no significant differences in terms of serum sodium, potassium, urea, uric acid levels and creatinine clearance between girls and boys. Nine patients had ureteropelvic junction obstruction (UPJO). Among all 60 patients only one patient developed chronic renal failure. At the end of follow up period none of the patients had proteinuria or hypertension. CONCLUSIONS: Horseshoe kidney require careful physical examination. Concomitant urinary system anomalies may require surgical intervention and may result in renal scar related chronic kidney disease. Patients with horseshoe kidneys should be monitored closely and carefully. [ABSTRACT FROM AUTHOR]