Asymptotic and transient behaviour for a nonlocal problem arising in population genetics.

This work is devoted to the study of an integro-differential system of equations modelling the genetic adaptation of a pathogen by taking into account both mutation and selection processes. First, we study the asymptotic behaviour of the system and prove that it eventually converges to a stationary state. Next, we more closely investigate the behaviour of the system in the presence of multiple EAs. Under suitable assumptions and based on a small mutation variance asymptotic, we describe the existence of a long transient regime during which the pathogen population remains far from its asymptotic behaviour and highly concentrated around some phenotypic value that is different from the one described by its asymptotic behaviour. In that setting, the time needed for the system to reach its large time configuration is very long and multiple evolutionary attractors may act as a barrier of evolution that can be very long to bypass. [ABSTRACT FROM AUTHOR]