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Outcomes of a Peri- and Postoperative Management Protocol for Non-TB Mycobacteria in Lung Transplant Recipients.

Authors :
Hirama, Takashi
Singer, Lianne G.
Brode, Sarah K.
Marras, Theodore K.
Husain, Shahid
Source :
CHEST. Aug2020, Vol. 158 Issue 2, p523-528. 6p.
Publication Year :
2020

Abstract

To the Editor: Non-TB mycobacteria (NTM) are becoming increasingly recognized as clinically significant pathogens in lung transplant recipients (LTRs).[[1]] Owing to advanced pulmonary disease among lung transplantation (LTX) candidates, patients could have a history of remote or current NTM-pulmonary disease (PD), or it could be detected incidentally after being listed for LTX. Posttransplantation NTM-PD and Overall Outcome In follow up until December 2017, posttransplantation NTM-PD developed in 11.1% of LTRs (2/18 patients) with peritransplantation NTM-PD (11 and 12 months after NTM management protocol, respectively) vs 6.6% of LTRs (14/212 patients) without peritransplantation NTM-PD (median, 10 months after transplantation; P =.362). To sum up, patients with NTM-PD diagnosed at the time of LTX and treated according to the protocol were safely managed and did not experience significantly greater rates of post-transplant NTM-PD, CLAD and survival. [Extracted from the article]

Details

Language :
English
ISSN :
00123692
Volume :
158
Issue :
2
Database :
Academic Search Index
Journal :
CHEST
Publication Type :
Academic Journal
Accession number :
144772625
Full Text :
https://doi.org/10.1016/j.chest.2020.01.056