Tandem Phospha‐Michael Addition/N‐Acylation/ Intramolecular Wittig Reaction of aza‐o‐Quinone Methides: Approaches to 2,3‐Disubstituted Indoles.

Authors :: Hua, Ting‐Bi
Chao, Fei
Wang, Long
Yan, Chen‐Yang
Xiao, Cong
Yang, Qing‐Qing
Xiao, Wen‐Jing
Source :: Advanced Synthesis & Catalysis. 7/16/2020, Vol. 362 Issue 13, p2615-2619. 5p.
Publication Year :: 2020
Abstract: A tandem phospha‐Michael addition/N‐acylation/intramolecular Wittig reaction of in situ formed aza‐o‐QMs is disclosed. This approach features high functional group tolerance and provides a convenient and practical access to biologically significant indole derivatives (37 examples, up to 91% yield) under mild reaction conditions. [ABSTRACT FROM AUTHOR]

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