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<break></break>4<italic>H</italic>-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4<italic>H</italic>-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.<break></break><break></break>4<italic>H</italic>-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4<italic>H</italic>-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.<break></break><break></break>4<italic>H</italic>-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4<italic>H</italic>-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.<break></break><break></break>4<italic>H</italic>-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4<italic>H</italic>-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.<break></break><break></break>4<italic>H</italic>-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4<italic>H</italic>-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.<break></break> [ABSTRACT FROM AUTHOR]