45th Annual Meeting of the Southern Pediatric Neurology Society.

Three patients were tested for respiratory viruses, including influenza A/B, during their initial attacks, and 1 patient with monophasic acute disseminated encephalomyelitis tested positive for adenovirus. Patients <5 years of age were less likely to have urologic, gastrointestinal, and neurologic or orthopedic symptoms; males were less likely to have urologic symptoms; those with fatty fila were more likely to have gastrointestinal and neurologic or orthopedic symptoms; patients with thickened fila were less likely to have urologic symptoms; patients with low-lying coni were less likely to have urologic and gastrointestinal symptoms. Though our patient had not previously been given a diagnosis of Ohtahara syndrome, her seizure semiology and age of onset in conjunction with a history of profound developmental delay and a distinct EEG pattern of suppression-burst noted since infancy, leads us to a diagnosis of Ohtahara syndrome. Our case demonstrates the oldest Ohtahara syndrome patient in literature to have persistent suppression-burst pattern on EEG, a unique case of Ohtahara syndrome that has persisted into childhood as well as the second reported patient with Ohtahara syndrome and a KCNT1 mutation. [Extracted from the article]