Nörosteroidler: Psikofarmakolojik ve Davranışsal Etkileri.

Steroids are known to act via genomic mechanism by binding to their own intracellular receptors. In addition to the steroids which are synthesized in the endocrine organs and able to easily cross to the brain, some steroids have been reported to be synthesized in the brain, to change neuronal excitability and to affect brain functions by interacting with the receptors on the surface of the neuronal membrane such as ligand-gated ion channels. Such steroids are called neuroactive steroids (neurosteroids). In this article, the psychopharmacological effects of the neurosteroids are summarized and their roles in the neuropsychiatric disorders are reviewed in detail. [ABSTRACT FROM AUTHOR]