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Neurocognitive and behavioural profile in Panayiotopoulos syndrome.
- Source :
-
Developmental Medicine & Child Neurology . Aug2020, Vol. 62 Issue 8, p985-992. 8p. - Publication Year :
- 2020
-
Abstract
- <bold>Aim: </bold>To determine neurocognitive performance and behavioural problems in children with Panayiotopoulos syndrome.<bold>Method: </bold>All 18 children (10 females, 8 males; mean age 4y 7mo; SD 1y 10mo) diagnosed with Panayiotopoulos syndrome at the Kempenhaeghe Epilepsy Center in the Netherlands between 2010 and 2017 were analysed retrospectively. All underwent a neuropsychological/behavioural assessment, an academic assessment, and a 24-hour electroencephalogram.<bold>Results: </bold>Mean full-scale IQ (93.5; range 76-123; p=0.04) and performance IQ (93.2; range 76-126; p=0.04) were within the normal range, although significantly lower compared to the normative mean. Verbal IQ (96.3; range 76-118) and processing speed (96.1; range 74-114) were not significantly lower. Simple auditory/visual reaction times, visual attention, visual-motor integration, and verbal memory were significantly lower compared to normative values. On average, patients with Panayiotopoulos syndrome were 8 months behind in arithmetic speed and 11 months behind in reading speed for the number of months in school. Behavioural questionnaires revealed significantly higher scores on reported internalizing behavioural problems.<bold>Interpretation: </bold>Children with Panayiotopoulos syndrome demonstrated diffuse cognitive dysfunction in full-scale IQ, performance IQ, visual attention, visual-motor integration, and verbal memory. A high incidence of internalizing behavioural problems was reported. This strongly suggests neuropsychological and behavioural comorbidity in children with Panayiotopoulos syndrome.<bold>What This Paper Adds: </bold>Children with Panayiotopoulos syndrome are at risk for cognitive deficits in various cognitive domains. Children with Panayiotopoulos syndrome are also prone to internalizing behavioural problems. Mild-to-severe academic underachievement was present in more than half of the children with Panayiotopoulos syndrome. [ABSTRACT FROM AUTHOR]
- Subjects :
- *VERBAL memory
*ACADEMIC underachievement
*MENTAL arithmetic
*SYNDROMES
*EPILEPSY & psychology
*COGNITION disorders
*RESEARCH
*EPILEPSY
*RESEARCH methodology
*RETROSPECTIVE studies
*EVALUATION research
*MEDICAL cooperation
*NEUROPSYCHOLOGICAL tests
*COMPARATIVE studies
*RESEARCH funding
*EDUCATIONAL attainment
*PSYCHOLOGICAL factors
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 00121622
- Volume :
- 62
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Developmental Medicine & Child Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 144337163
- Full Text :
- https://doi.org/10.1111/dmcn.14417