Back to Search Start Over

Prevalence of Sjögren's syndrome in the general adult population in Spain: estimating the proportion of undiagnosed cases.

Prevalence of Sjögren's syndrome in the general adult population in Spain: estimating the proportion of undiagnosed cases.

Authors :
Narváez, Javier
Sánchez-Fernández, Simón Ángel
Seoane-Mato, Daniel
Díaz-González, Federico
Bustabad, Sagrario
Source :
Scientific Reports. 6/30/2020, Vol. 10 Issue 1, p1-10. 10p.
Publication Year :
2020

Abstract

To estimate the prevalence of Sjögren's syndrome (SS) in the adult Spanish population we performed a population-based multicenter cross-sectional study. Cases were defined by the American-European Consensus Group criteria proposed in 2002. A total of 4,916 subjects aged 20 years or over were included. The estimated prevalence of SS (including primary and secondary forms) in the adult population in Spain was 0.33% (95% CI 0.21–0.53). Extrapolating to the total population of the country aged ≥ 20 years (around 37.7 million persons), there would be around 125,000 cases of SS in Spain. Considering only primary SS, the estimated prevalence was 0.25% (95% CI 0.15–0.43) or 1 person in 400. The prevalence of primary SS in Spain is comparable to that reported in other European studies with a similar design and diagnostic criteria. Based on these results, primary SS could not be considered a rare (orphan) disease. Only 50% of cases had already been diagnosed with SS prior EPISER 2016 study, confirming the existence of a non-negligible proportion of undiagnosed cases in the general population. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
10
Issue :
1
Database :
Academic Search Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
144315525
Full Text :
https://doi.org/10.1038/s41598-020-67462-z