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COMPARISON OF DEXMEDITOMIDINE AND PROPOFOL FOR HEMODYNAMIC AND RECOVERY CHARACTERISTICS IN DILATATION AND CURETTAGE.

Authors :
Farrukh, Raza
Awan, Waseem Sadiq
Khan, Ahmed Hassan
Rana, Asaad Rizwan
Jilani, Ahmed Aziz
Mahmood, Khalid
Source :
Professional Medical Journal. 2020, Vol. 27 Issue 6, p1244-1248. 5p.
Publication Year :
2020

Abstract

Objectives: To evaluate the hemodynamic and recovery characteristics of dexmeditomidine and propofol in dilatation and curettage. Study Design: Randomized control trial. Setting: Department of Anaesthesia, DHQ Teaching Hospital Sargodha. Period: March 2016 to December 2017. Material & Methods: Patients undergoing dilatation & curettage were randomly divided into two groups, group P received IV propofol 1.5mg/kg slowly over 5 min and group D received dexmeditomidine at a loading dose of 1µg/kg followed by 0.5 µg/kg/h. During the procedure blood pressure and heart rate were compared in both groups. In the recovery room, recovery time was compared in both groups by using modified aldrete score. Results: In Group D, the decrease in heart rate was statistically significant when compared with group P. Both groups showed a decrease in MAP but results were not statistically significant when compared in both groups. Patients in group D were discharged earlier from recovery room than group P and results were statistically significant. Conclusion: Dexmeditomodine provides better recovery than propofol so it is a suitable drug for day care minor surgical procedures. Similarly dexmeditomidine is superior to propofol by providing less respiratory depression intraopertaively. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10248919
Volume :
27
Issue :
6
Database :
Academic Search Index
Journal :
Professional Medical Journal
Publication Type :
Academic Journal
Accession number :
144307128
Full Text :
https://doi.org/10.29309/TPMJ/2020.27.06.4216