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Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression.

Authors :
Jian Han
An, Omer
HuiQi Hong
Hon Man Chan, Tim
Yangyang Song
Haoqing Shen
Sze Jing Tang
Lin, Jaymie Siqi
Hui En Ng, Vanessa
Jin Tai Tay, Daryl
Molias, Fernando Bellido
Pitcheshwar, Priyankaa
Hui Qing Tan
Yang, Henry
Leilei Chen
Source :
Science Advances. 6/17/2020, Vol. 6 Issue 25, p1-14. 14p.
Publication Year :
2020

Abstract

In this article, author uncover death associated protein 3 (DAP3) as a potent repressor of editing and a strong oncogene in cancer. It discusses the suppression of adenosine-to-inosine RNA editome by death associated protein 3 (DAP3) promotes cancer progression. It mentions the negative regulation of editing mechanism by which DAP3 promotes cancer development.

Details

Language :
English
ISSN :
23752548
Volume :
6
Issue :
25
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
144232889
Full Text :
https://doi.org/10.1126/sciadv.aba5136