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Genetic Heterogeneity of Australian Candida auris Isolates: Insights From a Nonoutbreak Setting Using Whole-Genome Sequencing.
- Source :
-
Open Forum Infectious Diseases . May2020, Vol. 7 Issue 5, p1-5. 5p. - Publication Year :
- 2020
-
Abstract
- Whole-genome sequencing clustered Australian Candida auris isolates from sporadic cases within clade III. Case isolates were genomically distinct; however, unexpectedly, those from 1 case comprised 2 groups separated by >60 single nucleotide polymorphisms (SNPs) with no isolate being identical, in contrast to outbreaks where isolates from any 1 individual have differed by <3 SNPs. Multidrug resistance was absent. High within-host genetic heterogeneity should be considered when investigating C. auris infections. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SINGLE nucleotide polymorphisms
*CANDIDA
*MULTIDRUG resistance
*HETEROGENEITY
Subjects
Details
- Language :
- English
- ISSN :
- 23288957
- Volume :
- 7
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Open Forum Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 143827179
- Full Text :
- https://doi.org/10.1093/ofid/ofaa158