A VGA Linearity Improvement Technique for ECG Analog Front-End in 65nm CMOS.

This paper presents a 65 nm CMOS low-power, highly linear variable gain amplifier (VGA) suitable for biomedical applications. Typical biological signal amplitudes are in the 0.5–100 mV range, and therefore require circuits with a wide dynamic range. Existing VGA architectures mostly exhibit a poor linearity, due to very low local feedback loop-gain. A technique to increase the loop-gain has been explored by adding additional feedback to the tail current source of the input differential pair. Stability analysis of the proposed technique was undertaken with pole-zero analysis. A prototype of Analog Front End (AFE) has been designed to provide 25–50 dB gain, and post-layout simulations showed a 15 dB reduction in the harmonic distortion for 20 mV pk-pk input signal compared to the conventional architecture. The circuit occupies 3,108 μ m2 silicon area and consumes 0.43  μ A from a 1.2 V power supply. [ABSTRACT FROM AUTHOR]