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Comparative antibacterial and antifungal activities of sulfur nanoparticles capped with chitosan.
- Source :
-
Microbial Pathogenesis . Jul2020, Vol. 144, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- The antimicrobial activity of sulfur nanoparticles (SNPs) was compared with elemental sulfur and sulfur-containing salts (sodium thiosulfate and sodium metabisulfite) against bacteria (Escherichia coli , Staphylococcus aureus) and fungi (Aspergillus flavus , Candida albicans) using the paper disc, broth microdilution, and time-kill assay methods. The results of the paper disc and MIC tests showed stronger antimicrobial activity of SNPs compared to the elemental sulfur and sulfur-containing salts. SNPs showed more potent activity against bacteria than fungi. Among the test microorganisms, E. coli (Gram-negative) was the most susceptible to SNPs, followed by S. aureus (Gram-positive), C. albicans (yeast), and A. flavus (mold). Scanning electron micrographs of microorganisms treated with SNPs showed different cell disruption patterns depending on the type of microorganisms. Image 1 • Chitosan-capped sulfur nanoparticles (SNPs) were prepared by the reduction of sodium thiosulfate. • Antimicrobial activity of SNPs was compared with elemental sulfur and S-containing salts. • Agar diffusion, MIC/MBC(MFC), time-kill assay for bacteria and fungi were determined. • SNPs showed stronger antibacterial and antifungal activity than elemental S and S-salts. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08824010
- Volume :
- 144
- Database :
- Academic Search Index
- Journal :
- Microbial Pathogenesis
- Publication Type :
- Academic Journal
- Accession number :
- 143558907
- Full Text :
- https://doi.org/10.1016/j.micpath.2020.104178