CARACTERISTIQUES DU PALUDISME GRAVE CHEZ LES ENFANTS DE 0 à 5 ANS A L'HOPITAL DE SIKASSO AU MALI.

In Mali, malaria is a major public health problem. The region of Sikasso is classified according to the geo-climatic facies as a zone with a long seasonal transmission of malaria greater than 6 months. Objective: To describe the epidemiological, clinical and therapeutic characteristics of children aged 0-5 years hospitalized for severe malaria in the pediatric ward of the Sikasso hospital. Variables analyzed were epidemiological, clinical, paraclinical, therapeutic and evolutionary. Patients and Methods: This is a retrospective, 12-month (January-December 2014) cross-sectional study of all 0-5-year-olds hospitalized for severe malaria at the Sikasso Regional Hospital. Results: The hospital frequency of severe malaria was 55.82%. The age group of 12-35 months was the most concerned (45.3%). The peak frequency was in August (21.2%). Anemic, mixed (anemia and neurological) and neurological forms were the most frequent. Artéméther and quinine were the antimalarials used. The use of a blood transfusion was frequent (82.8%). The lethality was 10% and the mixed form (anemia and neurology) was the most lethal ((P<10-6). Conclusion: Malaria remains a national concern in Mali. Improving the quality of care and prevention must be a priority to reduce the lethality that remains high. [ABSTRACT FROM AUTHOR]