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Diagnostic approach in hepatic lymphoma: radiological imaging findings and literature review.
- Source :
-
Journal of Cancer Research & Clinical Oncology . Jun2020, Vol. 146 Issue 6, p1545-1558. 14p. - Publication Year :
- 2020
-
Abstract
- Purpose: Imaging manifestations of hepatic lymphoma, both primary (PHL) and secondary (SHL), are extremely variable and non-specific, but some features are useful diagnostic clues in an appropriate clinical setting. Through a PubMed search, we found several published reviews focused on PHL and SHL diagnosis. However, to the best of our knowledge, few of them encompass a comprehensive analysis of all the diagnostic tools and relative radiological findings. The aim of this review is to provide a description of the radiological features of both PHL and SHL, by critically analyzing the available literature. Materials and methods: An extensive review of published literature along with a description of personal case series of both PHL and SHL has been conducted. Results: SHL can be easily diagnosed with imaging techniques, as it is usually associated with node disease. On the contrary the diagnosis can be a challenge in PHL, often mimicking HCC or liver metastasis of adenocarcinoma. In this context, multiparametric MRI plays a fundamental role in the differential diagnosis. Both for PHL and SHL, liver involvement presents as solitary or multiple lesions or as diffuse infiltrative disease. Conclusion: PHL and SHL may be correctly characterized using different radiological techniques. Both CT and MRI have showed a good correlation with histology, as they permit to distinguish between lymphomatous tissue, and necrotic and fibrotic areas. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LITERATURE reviews
*LYMPHOMAS
*LIVER metastasis
*DIFFERENTIAL diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 01715216
- Volume :
- 146
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Cancer Research & Clinical Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 143245415
- Full Text :
- https://doi.org/10.1007/s00432-020-03205-x