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Linking indirect effects of cytomegalovirus in transplantation to modulation of monocyte innate immune function.
- Source :
-
Science Advances . 4/24/2020, Vol. 6 Issue 17, p1-16. 16p. - Publication Year :
- 2020
-
Abstract
- The article focuses on the Cytomegalovirus (CMV), an important cause of morbidity and mortality in the immunocompromised host. It mentions that human monocytes infected with CMV do not effectively phagocytose fungal pathogens, a functional deficit which occurs with decreased expression of fungal recognition receptors; and also mentions that CMV modulates both immunosuppressive and immunostimulatory monocyte phenotypes.
Details
- Language :
- English
- ISSN :
- 23752548
- Volume :
- 6
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Science Advances
- Publication Type :
- Academic Journal
- Accession number :
- 142924573
- Full Text :
- https://doi.org/10.1126/sciadv.aax9856