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Protein nanocomposites: Special inferences to lysozyme based nanomaterials.

Authors :
Sarkar, Sharanya
Gulati, Khushboo
Mishra, Amit
Poluri, Krishna Mohan
Source :
International Journal of Biological Macromolecules. May2020, Vol. 151, p467-482. 16p.
Publication Year :
2020

Abstract

Protein nanocomposites have attracted considerable research interest in recent times owing to the combined advantageous properties of nanotechnology and proteins. Lysozyme holds enormous potential in various biomedical applications as it possesses antibacterial properties, anti-inflammatory, anti-cancer, and analgesic properties. Considering its multifunctional aspects, structural stability and ease of production and modification, special focus has been attributed to this protein. Nanocomposites have either been fabricated completely from lysozyme or have been conjugated to lysozyme considering its versatile biotechnological applications. The current review describes the recent advances of protein nanocomposites using lysozyme as a prime example. Along with the principles, techniques, and applications involved in protein based nanocomposites, this review also provides a comprehensive account of interactions between lysozyme and different nanoparticles. Numerous studies that have integrated the utilization of lysozyme and nanotechnology for a variety of applications have also been discussed at length. Unlabelled Image • Protein nanocomposites offer many advantages over traditional nanomaterials. • Nanotechnology oriented research has greatly benefitted from lysozyme. • Lysozyme based nanoparticles encase the antimicrobial property of lysozyme. • Lysozyme-nanoparticle interactions unraveled protein fibrillation mechanisms. • Lysozyme conjugated nanomaterials are effective sensors and delivery vehicles. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01418130
Volume :
151
Database :
Academic Search Index
Journal :
International Journal of Biological Macromolecules
Publication Type :
Review
Accession number :
142851744
Full Text :
https://doi.org/10.1016/j.ijbiomac.2020.02.179