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Depression and Sexual Trauma Among Adolescent Girls and Young Women in HIV-Prevention Research in Tanzania.
- Source :
-
Maternal & Child Health Journal . May2020, Vol. 24 Issue 5, p620-629. 10p. 3 Charts, 2 Graphs. - Publication Year :
- 2020
-
Abstract
- Purpose: Clinical trials are necessary to test HIV-prevention strategies among adolescent girls and young women in sub-Saharan Africa. Psychosocial risk factors that increase girls' and young women's vulnerability for HIV may also impact their experiences in clinical trials. A better understanding of psychosocial risks among girls and young women enrolled in HIV-prevention research is needed. This analysis explores depression and sexual trauma among adolescent girls and young women enrolled in a mock microbicide trial in Tanzania. Methods: We collected cross-sectional data from 135 HIV-negative adolescent girls and young women between 15 and 21 in Dar es Salaam, Tanzania enrolled in a mock microbicide trial. Depression, sexual behavior, and sexual trauma were measured. Sexual trauma and demographic variables were entered into a multivariate binomial logistic regression model predicting depression. Findings: Overall, 27% of participants had moderate-to-severe depression. The most commonly endorsed items were anhedonia (lack of interest/pleasure) and low mood, which were reported by 78% of participants. Thoughts of suicide or self-harm were endorsed by 17% of participants. Coerced/forced first sex was reported by 42% of participants. Participants reporting coerced/forced first sex had 3.16 times the likelihood of moderate-to-severe depression. Conclusions: Depression and coerced/forced sex were common among participants in an HIV-prevention mock clinical trial in Tanzania. When enrolling adolescent girls and young women in HIV-prevention trials in sub-Saharan Africa, our research suggests the need for a trauma-informed approach, referrals for trauma and depression, and interventions that address the impact of depression and trauma on HIV prevention, clinical trial adherence, and clinical outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SEXUAL trauma
*HIV prevention
*CONTROL (Psychology)
*ANALYSIS of variance
*CHI-squared test
*CONFIDENCE intervals
*STATISTICAL correlation
*MENTAL depression
*FISHER exact test
*INFORMED consent (Medical law)
*MENTAL health
*MULTIVARIATE analysis
*QUESTIONNAIRES
*RESEARCH funding
*SAFETY
*STATISTICAL sampling
*SEX crimes
*STATISTICS
*LOGISTIC regression analysis
*HUMAN research subjects
*CROSS-sectional method
*DATA analysis software
*DESCRIPTIVE statistics
*ADOLESCENCE
*ADULTS
Subjects
Details
- Language :
- English
- ISSN :
- 10927875
- Volume :
- 24
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Maternal & Child Health Journal
- Publication Type :
- Academic Journal
- Accession number :
- 142815855
- Full Text :
- https://doi.org/10.1007/s10995-020-02888-5