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Acute treatment patterns in patients with migraine newly initiating a triptan.
- Source :
-
Cephalalgia . Apr2020, Vol. 40 Issue 4, p437-447. 11p. - Publication Year :
- 2020
-
Abstract
- <bold>Background: </bold>Triptans are the most commonly used acute treatment for migraine. This study evaluated real-world treatment patterns following an initial triptan prescription to understand refill rates and use of non-triptan medications for the acute treatment of migraine.<bold>Methods: </bold>Commercially-insured adult patients over 18 years of age with a triptan prescription between 1/1/2013 to 31/12/2013 were identified from the Optum Clinformatics™ Data Mart database, with date of the first triptan fill designated as index date. Inclusion was limited to those with no fills for a triptan in the 12 months prior to index date (i.e. new users or initiators of triptans) and continuous enrollment in the 12 months pre- and 24 months post-index date. Fills for index triptan, non-index triptan, and other acute treatments for migraine were assessed for up to 24 months post-index.<bold>Results: </bold>Among 10,509 patients, 50.8% did not refill the initial triptan within 12 months and 43.6% did not refill within 24 months. In the 12 months post-index, 90.5% of patients used only one type of triptan, 8.4% used two different triptans, and 1.0% used three or more triptans. Among patients with and without a triptan refill, use of opioids (39% vs. 42%), non-steroidal anti-inflammatory drugs (22% vs. 22%), and butalbital-containing products (9% vs. 10%) were similar.<bold>Conclusion: </bold>More than half of those who newly initiated a triptan did not refill their initial prescription, and less than 1 in 10 used two or more triptans within 12 months. High rates of non-triptan acute medication use were found over 12 and 24 months of follow-up, most commonly opioids. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TRYPTAMINE
*MIGRAINE
*ANALGESICS
*RETROSPECTIVE studies
*LONGITUDINAL method
Subjects
Details
- Language :
- English
- ISSN :
- 03331024
- Volume :
- 40
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Cephalalgia
- Publication Type :
- Academic Journal
- Accession number :
- 142726351
- Full Text :
- https://doi.org/10.1177/0333102420905307