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Impact of Age on the Prognosis of Papillary Thyroid Carcinoma.
- Source :
-
Archives of Iranian Medicine (AIM) . Mar2020, Vol. 23 Issue 3, p169-174. 6p. - Publication Year :
- 2020
-
Abstract
- Background: Papillary thyroid carcinoma (PTC) is a common subtype of thyroid carcinoma with a rising incidence rate. The purpose of this study was to provide a better understanding of age and PTC using the Surveillance, Epidemiology, and End Results (SEER) Program. Methods: The study derived patients' information from the SEER Program (2010-2015). Chi-square or Fisher exact tests, and Kaplan-Meier method were used to analyze survival. Prognostic factors associated with survival were analyzed by Cox multivariate regression. Results: A total of 1738 records were included from SEER, with 1079 PTC in the age group <55 years, and 659 PTC in the age group ≥55 years. The 5-year survival rate was 94% and the overall survival (OS) curve in different age groups indicated that patients younger than 55yr have a longer survival time (P < 0.05). In multivariate Cox regression, age, M stage and surgery treatment were independent risk factors (P < 0.05). Regarding PTC-specific survival, age and surgery treatment were the two main independent prognostic factors in multivariate regression. However, AJCC and M stage were not in the disease specific survival. Conclusion: Age is a prognostic factor in OS and PCT specific survival. AJCC I stage and surgery treatment are also significant in predicting prognosis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AGE distribution
*CHI-squared test
*CONFIDENCE intervals
*DATABASES
*FISHER exact test
*MEDICAL information storage & retrieval systems
*PROBABILITY theory
*PROGNOSIS
*OPERATIVE surgery
*SURVIVAL analysis (Biometry)
*THYROID gland tumors
*PROPORTIONAL hazards models
*PAPILLARY carcinoma
*DATA analysis software
*DESCRIPTIVE statistics
*KAPLAN-Meier estimator
Subjects
Details
- Language :
- English
- ISSN :
- 10292977
- Volume :
- 23
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Archives of Iranian Medicine (AIM)
- Publication Type :
- Academic Journal
- Accession number :
- 142593315