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Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.

Authors :
Huc, Laurence
Sparfel, Lydie
Rissel, Mary
Dimanche-Boitrel, Marie-Thérèse
Guillouzo, André
Fardel, Olivier
Lagadic-Gossmann, Dominique
Source :
FASEB Journal. Feb2004, Vol. 18 Issue 2, p344-346. 3p. 1 Diagram, 2 Graphs.
Publication Year :
2004

Abstract

Presents a study on the effects of polycyclic aromatic hydrocarbons (PAH) on intracellular pH in liver epithelial cells. Induction of an early intracellular alkalinization by PAH; Involvement of NHE-1-related transient alkalinization in benzo(a)pyrene-induced apoptosis of liver epithelial cells; Conclusion of the study.

Details

Language :
English
ISSN :
08926638
Volume :
18
Issue :
2
Database :
Academic Search Index
Journal :
FASEB Journal
Publication Type :
Academic Journal
Accession number :
14252183
Full Text :
https://doi.org/10.1096/fj.03-0316fje