CFTR Channel Pharmacology: Novel Pore Blockers Identified by High-throughput Screening.

Comments on the findings of a study appearing in the August 2004 issue of the "Journal of General Physiology" regarding cystic fibrosis transmembrane conductance regulator (CFTR) pharmacology. Absence of potent, specific inhibitors of anion channels and implications for CFTR pharmacology studies; Discovery of a glycine hydrazides and its impact on CFTR inhibitors; Relationship between the chemical structure of glycine hydrazides and CFTR inhibition.