Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR-and EGFRvIII-overexpressing tumor cells.

Presents the results of a study on epidermal growth factor receptor (EGFR)-targeted immunoliposomes (IL) with the potential to provide intracellular drug delivery to EGFR and EGFRvIII-overexpressing tumor cells. Details of the preparation of lipososomes; Background on the cell lines used in the study, including human glioblastoma U-87; Characteristics of the cytotoxicity of Il containing doxorubicin and vinorelbine against EGFR overexpressing cells.