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Allosteric GABAA Receptor Modulators—A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility †.
- Source :
-
Molecules . Feb2020, Vol. 25 Issue 4, p999. 1p. 59 Diagrams, 1 Graph. - Publication Year :
- 2020
-
Abstract
- GABAA receptor modulators are structurally almost as diverse as their target protein. A plethora of heterocyclic scaffolds has been described as modulating this extremely important receptor family. Some made it into clinical trials and, even on the market, some were dismissed. This review focuses on the synthetic accessibility and potential for library synthesis of GABAA receptor modulators containing at least one heterocyclic scaffold, which were disclosed within the last 10 years. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HETEROCYCLIC chemistry
*CLINICAL trials
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 25
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 142148448
- Full Text :
- https://doi.org/10.3390/molecules25040999