Evaluation Of Clinical Profile and outcome of H1N1 (Swine Flu) Patients at A Tertiary Care Hospital -- MAMC Agroha.

Background: The hemagglutinin type 1 and neuraminidase type 1 (H1N1) virus known as swine flu virus resulted from a triple genetic re-assortment of human, avian and swine influenza viruses. It can lead to mild flu to life-threatening pneumonia, bronchitis, acute respiratory distress syndrome and even death. Aim of this study is to assess clinical profile and outcome of patients infected with H1N1 Virus. Material and Methods: This retrospective study was performed at Maharaja Agarsen Medical College, Agroha from December 2018- Feburary 2019. Data of all the patients including clinical history and relevant investigations was collected from Indoor Files. Samples of suspected patients were collected and tested for real time PCR. Results: Out of 69 suspected patients, samples tested for RTPCR 32 (46.4%) cases were identified as positive for H1N1. Overall swine positivity was higher in females than males. Fever was the most common clinical symptom affecting 31(96.8%) patients followed by cough 28 (87.5%) and breathlessness 17(65.6%). Of all the positive patients, 23 (71.9%) patients survived the disease while 6 (18.8%) patients expired. Conclusion: Fever, cough and breathlessness were the common presenting symptoms of swine flu. Early diagnosis and prompt initiation of treatment is the only way to reduce the disease progression and mortality. Patients with comorbid conditions require attention as clinical course can be unpredictable. [ABSTRACT FROM AUTHOR]