Synthesis, crystal structure, bovine serum albumin binding studies of 1,2,4-triazine based copper(I) complexes.

A series of new copper complexes have been synthesized and completely characterized by pivotal analytical techniques. The coordination geometry around copper(I) complex was best described as distorted tetrahedral geometry. The binding of bovine serum albumin with Cu(I) complexes are also been investigated. The Stern–Volmer analysis on quenching data exhibits the presence of the static quenching mechanism. The binding constants were calculated using modified Stern-Volmer, Lineweaver–Burk and Scatchard plots. All the complexes exhibit the binding constants in the order of 104. Thus, these results can contribute to the development of Cu(I) based drugs. • Triazine based Copper(I) Complexes were designed and synthesized. • The coordination geometry of Cu(I) complex was described as distorted tetrahedral. • The binding of bovine serum albumin with Cu(I) complexes was studied. [ABSTRACT FROM AUTHOR]