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Outcome of ICSI pregnancies with spontaneous loss of a co‐twin compared with singleton ICSI pregnancies: Single center experience.
- Source :
-
Journal of Obstetrics & Gynaecology Research . Mar2020, Vol. 46 Issue 3, p445-450. 6p. 1 Diagram, 4 Charts. - Publication Year :
- 2020
-
Abstract
- Aim: To compare the outcome of intracytoplasmic sperm injection (ICSI) pregnancies complicated by spontaneous loss of a dichorionic co‐twin with that of singleton ICSI pregnancies. Methods: The study group included dichorionic ICSI pregnancies with co‐twin loss (n = 33) and the control group included ICSI pregnancies with a singleton from the beginning (n = 327). Primary outcome measures were obstetric complications, including preterm delivery, newborn small for gestational age, gestational diabetes, gestational hypertensive disorders and abruptio placenta; admission to neonatal intensive care unit (NICU) and perinatal mortality observed in the study and control groups. Statistical analysis was performed using spss for Windows, version 22.0. Results: In the study group, there were 26 cases of first trimester (early) and 7 cases of second or third trimester (late) co‐twin losses. Mean gestational age at delivery and mean birth weight were significantly lower in the whole study group compared to control (P < 0.05). Preterm delivery and NICU admission rates were significantly higher in the whole study group, compared to control (39.3% vs 14.6% and 36.36% vs 11.69% respectively, P < 0.05), but did not show significant difference between early loss subgroup and control (P > 0.05). Preterm delivery rate was significantly higher in the late loss subgroup compared to the early loss subgroup (85.71% vs 26.92% P < 0.05). Conclusion: Loss of a co‐twin in dichorionic ICSI pregnancies is associated with increased risk of preterm birth. This risk is significantly higher in cases with late loss compared to the early loss cases. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BIRTH size
*COMPARATIVE studies
*GESTATIONAL diabetes
*FERTILIZATION in vitro
*HYPERTENSION in pregnancy
*PREMATURE infants
*INFANT mortality
*EVALUATION of medical care
*NEONATAL intensive care
*HEALTH outcome assessment
*PREGNANCY
*PREGNANCY complications
*RISK assessment
*TWINS
*NEONATAL intensive care units
*DATA analysis software
*DESCRIPTIVE statistics
*ABRUPTIO placentae
Subjects
Details
- Language :
- English
- ISSN :
- 13418076
- Volume :
- 46
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Obstetrics & Gynaecology Research
- Publication Type :
- Academic Journal
- Accession number :
- 141999432
- Full Text :
- https://doi.org/10.1111/jog.14177