Relationship between immune parameters during a severe exacerbation in allergic asthmatic children and asthma outcomes in the following year.

The aim of this study was to explore this relationship in the first year following severe exacerbation in our previously cited cohort of school-aged children.[7] We also compared asthma characteristics recorded at baseline and asthma outcomes at 1 year. At 1-year visit, patients were classified into three groups according to asthma outcomes: (a) good responders: no exacerbation during follow-up and well-controlled asthma according to GINA guidelines; (b) partial responders: no more than one severe exacerbation during follow-up and/or partly controlled asthma; (c) poor responders: >=2 severe exacerbations during follow-up and/or uncontrolled asthma. We also observed that control and lung function evaluated 8 weeks after an asthma exacerbation might be predictive of future asthma outcomes. The influence of asthma control on the severity of virus-induced asthma exacerbations. [Extracted from the article]