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Synthesis and characterization of molecularly imprinted polymer microspheres functionalized with POSS.
- Source :
-
Applied Surface Science . May2020, Vol. 511, pN.PAG-N.PAG. 1p. - Publication Year :
- 2020
-
Abstract
- • Uniform porous PTX-MIP microparticles were prepared by RAFTPP. • The amounts of M−POSS significantly improved the pore structure of PTX-MIP. • The PTX-MIP exhibited good adsorption selectivity towards Paclitaxel. • The obtained PTX-MIP showed fast adsorption kinetics and reusability. A type of novel porous molecularly imprinted polymer (MIP) microspheres containing methacryl polyhedral oligomeric silsesquioxane (M−POSS) were synthesized through reversible addition-fragmentation chain transfer polymerization precipitation polymerization (RAFTPP). The obtained porous microspheres had narrow particle size distribution and regular spherical shape. The addition of M−POSS could not only largely enhance the structural stability but also increase the pore structure of MIPs. The composition and shape characteristic of the MIPs were characterized by FT-IR, CA, SEM, TGA, and N 2 adsorption–desorption isotherm. The binding properties and selectivity of the MIP and non-imprinted polymer (NIP) were demonstrated by adsorption capacity obtained based on HPLC absorption measurements. The results showed that the adsorption capacity of the paclitaxel imprinted polymer containing 85 mg M−POSS (PTX-MIP2) for PTX reached 17.24 mg g−1 after 200 min. A comparative study demonstrated that PTX-MIP2 possessed excellent selectivity towards PTX, which presented an imprinting factor of 3.17. Meanwhile, PTX-MIP2 could be reused five cycles with slight loss in adsorption capacity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01694332
- Volume :
- 511
- Database :
- Academic Search Index
- Journal :
- Applied Surface Science
- Publication Type :
- Academic Journal
- Accession number :
- 141903003
- Full Text :
- https://doi.org/10.1016/j.apsusc.2020.145506