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Comparison of the efficacy and safety of using 0.01% versus 0.03% bimatoprost for the treatment of eyebrow hypotrichosis: A randomized, double‐blind, split‐face, comparative study.
- Source :
-
Journal of Cosmetic Dermatology . Mar2020, Vol. 19 Issue 3, p714-719. 6p. - Publication Year :
- 2020
-
Abstract
- Background: Previous studies have proven the efficacy and safety of 0.01% and 0.03% bimatoprost for the treatment of eyebrow hypotrichosis; however, there is no comparison study between both concentrations. Aims: To compare the efficacy and safety between 0.01% and 0.03% bimatoprost for the treatment of eyebrow hypotrichosis. Patients/Methods: This prospective, randomized, double‐blind, split‐face clinical study was conducted in 30 patients with eyebrow hypotrichosis. Each side of eyebrow of individual patients was randomly assigned for 0.01% and 0.03% bimatoprost, applied on each eyebrow once daily. Eyebrow density, diameter, the Global Eyebrow Assessment scale, 7‐point rating scale, and patient satisfaction were evaluated. Side effects were also recorded. Results: Both 0.01% and 0.03% bimatoprost significantly improved eyebrow density and diameter (P <.05), although there were no statistically significant differences in changes in eyebrow density and diameter from baseline between both concentrations (P =.96 and.84, respectively). Additionally, patients significantly preferred 0.03% bimatoprost in terms of clinical improvement and satisfaction (P =.04 and.003, respectively). Conclusions: Both 0.01% and 0.03% bimatoprost are effective and safe for the treatment of eyebrow hypotrichosis. Bimatoprost 0.03% is superior to its 0.01% counterpart, albeit without statistical significance. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14732130
- Volume :
- 19
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Cosmetic Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 141676822
- Full Text :
- https://doi.org/10.1111/jocd.13079