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Technical Challenges Encountered During Chromatographic Method Transfers to Pharmaceutical Manufacturing Sites.

Authors :
Tattersall, Peter
Zang, Jia
Kleintop, Brent
Source :
LC-GC North America. Jan2020, Vol. 38 Issue 1, p40-49. 10p.
Publication Year :
2020

Abstract

The article discusses technical challenges encountered during chromatographic method transfers to pharmaceutical manufacturing sites. It mentions that genotoxic impurities has resulted in analytical control strategies increasingly utilizing analytical detection techniques outside of traditional quality control-friendly liquid chromatography–ultraviolet and gas chromatography–flame ionization detector instruments.

Details

Language :
English
ISSN :
15275949
Volume :
38
Issue :
1
Database :
Academic Search Index
Journal :
LC-GC North America
Publication Type :
Periodical
Accession number :
141655253