P.325 Childhood trauma does not explain altered brain network integration or segregation detected in schizophrenia.

Converging lines of evidence from epidemiological, genetic and neuroimaging studies highlight that childhood trauma can increase the risk for later development of schizophrenia; a major psychiatric disorder [1]. The brain's structural network organisation has been shown to be disrupted in schizophrenia [3] and previous neuroimaging studies report widespread cortico-subcortical grey and white matter impairments amongst individuals with childhood trauma [4]. [Extracted from the article]