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Echocardiographic E/A inversion and air trapping at rest are associated with an exaggerated blood pressure response in medically controlled hypertensives during bicycle ergometry.
- Source :
-
Cogent Medicine . Jan2019, Vol. 6 Issue 1, p1-9. 9p. - Publication Year :
- 2019
-
Abstract
- Exaggerated blood pressure response during exercise is a risk factor for cardiovascular disease, but is inhomogeneously defined in the literature. We used a novel approach by taking into account both workload and blood pressure to define exercise hypertension (systolic values > 200 mmHg at 100W). We examined medically controlled hypertensives (n = 373; mean age 56.7 ± 14.8 years) and their blood pressure response during bicycle ergometry. Exercise hypertension was inversely associated with E/A wave ratio but not E/E' during resting echocardiography (p = 0.045; p = 0.293). Functional air trapping (residual volume/total lung capacity, RV/TLC) was significantly higher in the group of exercise hypertensives (43.6% ± 11.6 vs. 38.1% ± 10.0; p = 0.005). Patients treated with renin-angiotensin aldosterone system (RAAS) blockers showed lower blood pressure response during exercise than those treated with calcium channel blockers (CCBs) and thiazides (both <0.001) and also displayed higher E/A (p = 0.023) and lower E/E' values (p = 0.042). We provide evidence that the easily accessible parameters E/A inversion and air trapping at rest could be used in clinical routine to screen for exercise-induced hypertension in medically controlled hypertensives. We also show that RAAS blockers have a more favorable effect on blood pressure response during exercise than CCBs and thiazides. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 2331205X
- Volume :
- 6
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Cogent Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 141193487
- Full Text :
- https://doi.org/10.1080/2331205X.2019.1707014