Change in Plasma Cryptococcal Antigen Titer Is Not Associated With Survival Among Human Immunodeficiency Virus–infected Persons Receiving Preemptive Therapy for Asymptomatic Cryptococcal Antigenemia.

The article discusses the World Health Organization guidelines for recommending cryptococcal antigen (CrAg) screening in blood for human immunodeficiency virus (HIV)-infected persons, who do not receive effective antiretroviral therapy. It mention the asymptomatic CrAg-positive patients being enrolled in the ORCAS study during fluconazole therapy.