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Glioma progression through synaptic activity.

Authors :
Lim-Fat, Mary Jane
Wen, Patrick Y.
Source :
Nature Reviews Neurology. Jan2020, Vol. 16 Issue 1, p6-7. 2p.
Publication Year :
2020

Abstract

Two new studies show that gliomas can manipulate normal elements of neuronal development and plasticity to create neuron–glia synapses, activation of which leads to glioma proliferation. Interventions that target the AMPA receptor could slow down tumour growth by altering this synaptic transmission. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17594758
Volume :
16
Issue :
1
Database :
Academic Search Index
Journal :
Nature Reviews Neurology
Publication Type :
Academic Journal
Accession number :
141026328
Full Text :
https://doi.org/10.1038/s41582-019-0290-1