Association between maternal carotenoid, vitamin A, and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life.

In this study, we found no association between maternal blood levels of carotenoids, vitamin A, and vitamin E at delivery with the development of allergen sensitization, eczema, rhinitis, and wheeze with use of nebulizer/inhaler in the offspring in first five years of life. To our knowledge, this is the first study with the longest follow-up of children, to have investigated relationships between objective measurements of carotenoids, vitamin A, and vitamin E in maternal blood with allergic outcomes in offspring up to five years old. The strengths of this study are the objective measurement of carotenoids, vitamin A, and vitamin E in maternal plasma, which are not subjected to recall bias. Vitamins A and E during pregnancy and allergy symptoms in an early childhood-lack of association with tobacco smoke exposure. [Extracted from the article]