深度水解蛋白配方奶在不同体重早产儿喂养中的临床效果观察.

Objective: To evaluate the clinical effect of extensively hydrolyzed formula (eHPF) on the early feeding of different weight premature infants. Methods: Premature infants treated in our hospital's neonatal ward from September 2017 to December 2018 were studied, including 62 very low birth weight (weight between 1000- 1500g) and 100 low birth weight (weight between 1500-2000g). They were randomly divided into two groups: extensively hydrolyzed formula group (observed group) and preterm formula (control group), and concretely very low birth weight were started feeding after 12 hours and changed to preterm formula after 2 weeks and very low birth weight were feeding 12 hours and changed to preterm formula after 1 weeks. The clinical effect were compared between different weight premature infants early feeding. The recovery time to birth weight, weight growth, retention time to stomach tube, time to reach full enteral nutrition, hospitalization days, feeding tolerance, the incidence of extrauterine growth retardation(EUGR) and ureanitrogon, alkaline phosphatase were observed and compared between two groups. Results: Compared with the control group, the recovery time to birth weight, full enteral feeding, retention time to stomach tube and hospitalization day of treatment group were markedly shorter, (P<0.05). The weight growth of observed group was superior to that of the preterm formula group, the feeding tolerance and the incidence of extrauterine growth retardation(EUGR) were lower than control group(P<0.05). There was no difference in the ureanitrogon, alkaline phosphatase between two groups (P>0.05). Conclusion: Extensively hydrolyzed formula is obviously better than that of preterm formula in the early feeding of premature infants with different body weights, which is more conducive to the growth and development of premature infants. [ABSTRACT FROM AUTHOR]