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Electrochemical sensing of lactate by using an electrode modified with molecularly imprinted polymers, reduced graphene oxide and gold nanoparticles.

Authors :
Pereira, Thulio César
Stradiotto, Nelson Ramos
Source :
Microchimica Acta. Dec2019, Vol. 186 Issue 12, p1-10. 10p.
Publication Year :
2019

Abstract

This paper reports on a sensitive and selective electrochemical sensor for lactic acid. The sensor is based on molecularly imprinted polymers (MIP), obtained on glassy carbon electrode (GCE) modified with reduced graphene oxide and gold nanoparticles. The MIP was obtained by electropolymerization of the o-phenylenediamine (o-PD) on the modified surface of the GCE in the presence of lactic acid. The steps involving the GCE modification and MIP construction were characterized by cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy and atomic force microscopy. The results were evaluated using differential pulse voltammetry, using the hexacyanoferrate redox system as an electrochemical probe. Under optimized experimental conditions, the imprinted sensor has a linear response in the 0.1 nM to 1.0 nM lactic acid concentration range, with detection limit of 0.09 nM. The sensor exhibits excellent selectivity in the presence of molecules of similar chemical structure. It was applied for the selective determination of lactic acid in sugarcane vinasse. The recovery values ranged from 97.7 to 104.8%. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00263672
Volume :
186
Issue :
12
Database :
Academic Search Index
Journal :
Microchimica Acta
Publication Type :
Academic Journal
Accession number :
140622557
Full Text :
https://doi.org/10.1007/s00604-019-3898-3