Fabrication and Characterization of Nano-TCP Doped with Various Ions for Bone Implant Applications.

Calcium phosphate (CaP) based bioceramics are frequently used in dental and orthopedic field as bone grafts due to their chemical and structural similarities to the human hard tissues. Strontium (Sr2+), fluoride (F-) and chloride (Cl-) ions are known to play important role in bone and tooth microstructure. The aim of this study was to combine tri-calcium phosphates doped with strontium, chloride and fluoride ions. A precipitation procedure was applied for synthesizing pure and doped tricalcium phosphates. The undoped and doped samples were sintered at 1100°C for 1 h. Incorporation of the strontium (Sr+2) and chloride (Cl-) ions decreased the density of the samples while, the fluoride (F-) co-doped densities increased with respect to pure TCP. The XRD results revealed the existence of the α-TCP and β-TCP phases. SEM results confirmed the sintering temperature and amount of dopants had prominent effect on the grain sizes of the samples. [ABSTRACT FROM AUTHOR]