Frequency of readmission in Iranian heart failure patients within six months after discharge and its association with guideline directed medical treatment.

Background and Aims: Assessment of heart failure (HF) therapy based on guideline was less frequently performed. Objectives: In this study, we aimed to evaluate the frequency of readmission or mortality in HF patients according to guideline directed medical treatment. Materials and Methods: This retrospective cohort study was done from March 2016 to March 2017 in one of the tertiary heart centers located in Isfahan, named Chamran Hospital. A total of 503 patients with a diagnosis of HF were recruited in the research. Demographic data, prescribed medication, and para-clinic information were gathered during hospitalization period. The frequency of re-hospitalization and mortality was assessed 6 months after discharge, and its relation with aforementioned variables was evaluated. Results: The mean age of participants with the dominance of males (61.8%) was 70.8 ± 11.8 years. A total of 175 (34.8%) patients had been readmitted or died during 6-month follow-up. Participants with New York Heart Association (NYHA) functional class of IV and renal diseases had raised likelihood of re-hospitalization or death (odds ratio [OR]: 5.59, 95% confidence interval [CI] = 1.42-21.5, P = 001 and OR: 2.53, 95% CI = 1.11-5.79, P = 0.02, respectively). In contrast, individuals with heart rates (HR) of 80-100 beats/min showed decreased chance of adverse clinical outcomes compared to subjects with HRs of <60 beats/min (OR: 0.08, 95% CI = 0.009-0.77, P = 0.02). Conclusion: Our data suggested that HF patients having higher NYHA functional class or kidney problems and HRs of 80-100 beats/min had increased and decreased likelihood of readmission and mortality, respectively. Several longitudinal studies are required confirming these associations. [ABSTRACT FROM AUTHOR]