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A highly sensitive and selective "turn-on" fluorescent probe for detection of fleroxacin in human serum and urine based on a lanthanide functionalized metal–organic framework.
- Source :
-
Dalton Transactions: An International Journal of Inorganic Chemistry . 12/28/2019, Vol. 48 Issue 48, p17945-17952. 8p. - Publication Year :
- 2019
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Abstract
- Cation exchange, a facile and non-destructive post-synthetic modification method, is applied to [(Me)4N]2[Pb6K6(m-BDC)9(OH)2]·H2O (1) (1,3-H2BDC = 1,3-benzenedicarboxylic acid) to prepare a series of lanthanide functionalized metal–organic frameworks. The fluorescence properties of Ln3+@1 (Ln = Eu, Tb, Sm and Dy) are investigated. The results demonstrate that the framework of 1 is capable of sensitizing both Eu3+ and Tb3+ ions effectively. Remarkably, the rapid and stable fluorescence sensitization of Eu3+@1 can be observed in the presence of fleroxacin in aqueous solution, indicating that the hybrid system can be designed as a highly sensitive and selective probe for fleroxacin. As a novel "turn-on" fluorescent probe, Eu3+@1 is regarded as a promising candidate for applications in clinical diagnosis, due to its merits of high antidisturbance, chemical stability and a low detection limit (43.91 ng mL−1). In this paper, the practical application of luminescent Eu3+@1 is highlighted, and its possible sensing mechanism is also described. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14779226
- Volume :
- 48
- Issue :
- 48
- Database :
- Academic Search Index
- Journal :
- Dalton Transactions: An International Journal of Inorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 140273546
- Full Text :
- https://doi.org/10.1039/c9dt03830b