Back to Search
Start Over
Efficacy of "Pinggan Formula" in Controlling Acute Type B Aortic Dissection Perioperative Blood Pressure: A Randomized Controlled Clinical Trial.
- Source :
-
Evidence-based Complementary & Alternative Medicine (eCAM) . 11/15/2019, p1-9. 9p. 1 Diagram, 4 Charts. - Publication Year :
- 2019
-
Abstract
- Objective. To explore a new treatment that can proceed from the whole, control blood pressure smoothly and coordinate the treatment of multiple factors causing blood pressure fluctuations. Method. We conducted a single-center, double-blinded, and randomized controlled clinical trial. 48 patients with acute Type B aortic dissection were randomly assigned into two groups: the experimental group, who received pinggan formula treatment, and the control group, who received placebo treatment. The drug was taken orally after meals three times a day. Only when the patients' blood pressure fluctuated, conventional antihypertensive drugs were given to maintain the blood pressure within the target range and the dosage was recorded to convert the DDD value. Meanwhile, the international standardized score was used to evaluate the defecation, sleep, pain, anxiety, and depression of patients in the two groups during the hospitalization. Result. Univariate analysis was conducted on variables that might affect the assessment results, and it was found that grouping factors had a significant impact on the outcome variables, that is, after the intervention, the mean value of DDDs used in the perioperative period in the control group was 2.19 (0.38, 4.00). (P = 0.0219), defecation score (2.13 (1.59, 2.67); P < 0.0001), sleep score (0.95 (0.40, 1.50); P = 0.0014), pain score (1.77 (0.61, 2.93); P = 0.0045), depression score (4.04 (2.95, 5.12); and P < 0.0001) were significantly higher than that of the experimental group, and the difference was statistically significant. Conclusion. Pinggan formula has a clear therapeutic regulation effect on the overall hemodynamics of acute Stanford type B aortic dissection during the perioperative period and can be recommended as an auxiliary drug for conventional antihypertensive drugs at the current stage. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANXIETY diagnosis
*DIAGNOSIS of mental depression
*DEFECATION
*AORTIC dissection
*HEMODYNAMICS
*HERBAL medicine
*HOSPITAL care
*HYPERTENSION
*MEDICINAL plants
*CHINESE medicine
*SLEEP
*STATISTICS
*PAIN measurement
*RANDOMIZED controlled trials
*TREATMENT effectiveness
*BLIND experiment
*PERIOPERATIVE care
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 1741427X
- Database :
- Academic Search Index
- Journal :
- Evidence-based Complementary & Alternative Medicine (eCAM)
- Publication Type :
- Academic Journal
- Accession number :
- 139714875
- Full Text :
- https://doi.org/10.1155/2019/6432953