Non-HACEK Gram-negative bacillus endocarditis.

• Data on non-HACEK Gram-negative infective endocarditis is limited to case reports and case series. • Clinicians may encounter non-HACEK Gram-negative infective endocarditis in medical wards mostly because of the high number of intravascular interventions performed and elderly patients treated. • While environmental pathogens are pan-susceptible to antimicrobials, Klebsiella species endocarditis is associated with an increased risk of drug resistance. Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey. Mean age of patients was 53 (28–84) years, with a 23% case fatality. Nineteen (73%) of the 26 patients had at least one predisposing factor. The presence of a central venous catheter was the most common predisposing factor (7/26 patients). Pseud omonas aeruginosa (7/26 patients) and Escherichia coli (7/26 patients) were the most common pathogens. The median duration of the antibiotic therapy was 42 days (range 3–84 days). Surgical procedures were performed in 10 patients. The case fatality was similar in patients who did or did not undergo surgery (20% vs. 25%). [ABSTRACT FROM AUTHOR]