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Next-Generation HIV Pre-Exposure Prophylaxis Preferences Among Men Who Have Sex with Men Taking Daily Oral Pre-Exposure Prophylaxis.
- Source :
-
AIDS Patient Care & STDs . Nov2019, Vol. 33 Issue 11, p482-491. 10p. 4 Charts, 2 Graphs. - Publication Year :
- 2019
-
Abstract
- Next-generation forms of HIV pre-exposure prophylaxis (PrEP) currently in development, including long-acting injectables (LAIs), rectal microbicides (RMs), antibody infusions (AIs), and subdermal implants (SIs), may address barriers to daily oral PrEP uptake and adherence. The purpose of this study was to evaluate barriers to oral PrEP, preferences for next-generation PrEP modalities, sociodemographic characteristics and sexual behaviors associated with preferences, and reasons for wanting or not wanting each formulation among a sample of men who have sex with men (MSM). We administered a cross-sectional survey to a diverse sample of MSM currently taking oral PrEP (nā=ā108) at two sexually transmitted disease clinics. We used logistic multivariate analyses to explore preferences, relative to oral PrEP, for each formulation across sociodemographic and sexual behaviors. The most commonly endorsed barriers were finding a PrEP provider and making appointments to get PrEP. Participants were most likely to prefer the SI (45%), followed by the LAI (31%), pill (21%), RM (1%), and AI (1%). Black/African American and Hispanic/Latino MSM were more likely to prefer the LAI over daily oral PrEP (odds ratio: 2.45, 95% confidence interval: 0.86ā6.89), and sexual behaviors were most commonly associated with preference for the SI. Top reasons for wanting or not wanting each formulation were most commonly related to perceived ease of use. These findings demonstrate variations in preferences for next-generation PrEP modalities, highlighting a need to ensure comprehensive access to all formulations once they become available. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HIV prevention
*ANTIRETROVIRAL agents
*ANTI-infective agents
*BLACK people
*CONFIDENCE intervals
*CONTROLLED release drugs
*HISPANIC Americans
*IMMUNOGLOBULINS
*PREVENTIVE medicine
*MULTIVARIATE analysis
*ORAL drug administration
*RECTAL medication
*HUMAN sexuality
*SEXUALLY transmitted diseases
*SURVEYS
*LOGISTIC regression analysis
*CROSS-sectional method
*MEN who have sex with men
*PATIENTS' attitudes
*ODDS ratio
Subjects
Details
- Language :
- English
- ISSN :
- 10872914
- Volume :
- 33
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- AIDS Patient Care & STDs
- Publication Type :
- Academic Journal
- Accession number :
- 139474308
- Full Text :
- https://doi.org/10.1089/apc.2019.0093