Back to Search
Start Over
Evaluation of Serum Interleukin-6 Level in Vitiligo Patients before and after Phototherapy.
- Source :
-
Egyptian Journal of Hospital Medicine . 10/5/2019, Vol. 77 Issue 3, p5276-5278. 3p. - Publication Year :
- 2019
-
Abstract
- Background: Vitiligo is an acquired pigmentary disorder of the skin, resulting from a loss of functioning epidermal melanocytes. Multiple pathogenetic factors have been proposed, including the neural theory, genetic predisposition and impaired anti-oxidative defense. Objective: To evaluate the role of interleukin-6 in pathogenesis of vitiligo and the effect Narrow band-UVB on IL-6 serum levels. Patients and Methods: The study included 30 patients with vitiligo and 30 healthy controls. Each was submitted to thorough history taking, complete general, dermatological examinations including VASI score, and assessment of serum interleukin-6 before and after 16 sessions of NB-UVB. Results: Results of this study showed no statistical significant difference between patients and control as regard age and gender. Our study revealed a statistically significant difference between levels of IL-6 in patients group before and after therapy. Conclusion: Knowing exactly the role of IL-6 is important not only to clarify the pathogenesis of this disease, but also to improve the clinical course of vitiligo (i.e., disease stabilization and/or repigmentation) and the quality-of-life of patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- *VITILIGO
*INTERLEUKIN-6
*PHOTOTHERAPY
*SERUM
Subjects
Details
- Language :
- English
- ISSN :
- 16872002
- Volume :
- 77
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Egyptian Journal of Hospital Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 139417637