Gold‐Catalyzed Reaction of 2H‐Tetrazoles with Alkynes: Efficient Route to N‐Alkenylated Tetrazoles.

A gold‐catalyzed reaction of 2H‐tetrazoles with alkynes was described for the efficient synthesis of a variety of N‐alkenylated tetrazole derivatives, including N‐1 and N‐2 vinyl functionalized products which are readily isolated by column chromatography. The reaction mechanism was proposed to be a nucleophilic addition process to the alkyne motif activated by gold catalyst. The reaction features mild reaction condition, simple operation and high yields. [ABSTRACT FROM AUTHOR]