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Maternal Anemia and Coagulation/Fibrinolysis after Fetoscopic Laser Photocoagulation for Twin-to-Twin Transfusion Syndrome.
- Source :
-
Gynecologic & Obstetric Investigation . Sep2019, Vol. 84 Issue 5, p477-484. 8p. 3 Charts, 2 Graphs. - Publication Year :
- 2019
-
Abstract
- <bold>Aim: </bold>This study was performed to evaluate maternal changes in laboratory characteristics after fetoscopic laser photocoagulation (FLP) for twin-to-twin transfusion syndrome (TTTS).<bold>Methods: </bold>A retrospective review was conducted among 30 women with monochorionic diamniotic twin pregnancy with TTTS who underwent FLP at 16-26 weeks of gestation. Maternal laboratory parameters were measured before and after FLP.<bold>Results: </bold>The pre-FLP mean hemoglobin level (10.0 g/dL), hematocrit level (30.0%), platelet count (229 × 109/mL), fibrinogen level (461 mg/dL), and antithrombin activity (96.8%) decreased after FLP (8.5 g/dL, 25.5%, 204 × 109/mL, 403 mg/dL, and 83.6%, respectively) and returned to normal spontaneously within 2 weeks (9.6 g/dL, 29.4%, 293 × 109/mL, 460 mg/dL, and 102.4%, respectively). The D-dimer level before FLP (2.41 μg/mL) increased after FLP (4.28 μg/mL), and the elevated level was maintained for 2 weeks (3.24 μg/mL). The symptomatic venous thromboembolism (VTE) was not detected after FLP in any of the 30 patients. However, one woman had pulmonary embolism after subsequent cesarean section.<bold>Conclusion: </bold>Changes in maternal anemia and coagulation/fibrinolysis after FLP for TTTS returned to normal spontaneously within 2 weeks. Maternal elevation of D-dimer level after FLP might be a warning indicator of VTE. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03787346
- Volume :
- 84
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Gynecologic & Obstetric Investigation
- Publication Type :
- Academic Journal
- Accession number :
- 138733835
- Full Text :
- https://doi.org/10.1159/000499913